E cigarette use increases risk for developing major respiratory diseases Frontiers Inhalation of nicotine containing electronic cigarette vapor exacerbates the features of COPD by inducing ferroptosis in ENaC overexpressing mice E cig use associated with asthma, COPD in never smokers Stanton Glantz blog Vaping is not harmless. A new study from Johns Hopkins Medicine reveals that e cigarettes significantly increase the risk of COPD and high blood pressure. Our own Dr. Todd Hoopman shares firsthand accounts